WebAug 15, 2024 · Purpose: Although cisplatin plus radiotherapy is a standard treatment of locally advanced head and neck squamous cell carcinoma (LA-HNSCC), cisplatin contraindication is common. Radiation elicits and promotes tumor-directed immune stimulation, which may potentiate anti-PD-1 therapy. We provide the first efficacy report … WebAug 26, 2024 · In selected patients who after treatment initiation presented contraindications to concurrent cisplatin as a result of renal dysfunction, cisplatin replacement with weekly carboplatin area under the curve 2 …
Cisplatin Uses, Side Effects & Warnings - Drugs.com
WebContraindications to HBO • Absolute Contraindication • Untreated pneumothorax • Relative Contraindication • Seizure disorder (Not under control) • Fever > 102.5 F (39.2 … WebFeb 27, 2024 · Adjuvant chemoradiotherapy using intravenous bolus cisplatin 100 mg/m 2 every 3 weeks should be offered to patients with oral cavity cancer and extranodal extension in any positive node, regardless of the extent of extranodal extension and the number or size of involved nodes, and no contraindications to high-dose cisplatin (Type: evidence ... shun goosby photography
Common and Rare Side Effects for Cisplatin Vial - WebMD
WebConcurrent bolus cisplatin with radiation therapy (XRT) is a standard of care for the treatment of LA-HNSCC. Contraindications such as hearing loss, tinnitus, renal dysfunction or neuropathy are common. Radiation elicits and promotes tumor-directed immune-stimulation, which may potentiate anti-PD-1 therapy. Methods Weblow amount of sodium in the blood. low amount of potassium in the blood. hemolytic uremic syndrome, a condition that affects the kidney and the blood. anemia. decreased blood … WebCisplatin was given as a single intraperitoneal dose of 6 mg/kg, and HBO was applied for 60 min at 2.5 atm for six days. HBO alone did not alter any biochemical parameters or histopathological findings compared with the control group. Cisplatin increased serum urea and creatinine levels and caused severe histopathological injury. the out-laws